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Invitrogen™ TRBP Recombinant Rabbit Monoclonal Antibody (9E6C9)
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Product Code. 17207063 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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17207063 100 μL 100µL
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Product Code. 17207063 Supplier Invitrogen™ Supplier No. MA538184

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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse testis, Rat brain Immunogen sequence: RFIEIGSGTS KKLAKRNAAA KMLLRVHTVP LDARDGNEVE PDDDHFSIGV GSRLDGLRNR GPGCTWDSLR NSVGEKILSL RSCSLGSLGA LGPACCRVLS E.

TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRBP
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 9E6C9
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Gene TARBP2
Gene Accession No. P97473, Q15633, Q3SWU0
Gene Alias fj51e12; HAMAP-Rule:MF_03034}; LOQS; Prbp; PRM-1 RNA-binding protein; protamine-1 RNA-binding protein; RISC-loading complex subunit tarbp2; RISC-loading complex subunit TARBP2 {ECO:0000255; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; TAR (HIV-1) RNA binding protein 2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TARBP2; TARBP2 subunit of RISC loading complex; TARBP2, RISC loading complex RNA binding subunit; trans-activation responsive RNA-binding protein; trans-activation-responsive RNA-binding protein; TRBP; TRBP1; TRBP2; wu:fj51e12; zgc:63778
Gene Symbols TARBP2
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21357, 363006, 6895
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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