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Invitrogen™ TRHR Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA590309
This item is not returnable.
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Description
Immunogen sequence: YNLMSQKFRA AFRKLCNCKQ KPTEKPANYS VALNYSVIKE SDHFSTELDD ITVTDTYLSA TKVSFDDTCL ASEVSFSQS; Positive Samples: U-87MG; Cellular Location: Cell membrane, Multi-pass membrane protein.
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to widely express in the thyrotroph cells of the anterior pituitary.
Specifications
| TRHR | |
| Polyclonal | |
| Unconjugated | |
| TRHR | |
| MGC141920; Thyroliberin receptor; thyrotropin releasing hormone receptor; thyrotropin-releasing hormone receptor; TRH receptor; TRH1 Receptor; Trhr; TRH-R; TRH-R1 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 7201 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 0.81 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| P34981 | |
| TRHR | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 320-398 of human TRHR (NP_0032921). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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