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TRIB1 Mouse anti-Human, Clone: OTI1B11, liquid, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies TA805275
This item is not returnable.
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Description
TRIB1 also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.Specifications
| TRIB1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q96RU8 | |
| TRIB1 | |
| Full length human recombit protein of human TRIB1 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI1B11 | |
| Unconjugated | |
| TRIB1 | |
| C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 10221 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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