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Invitrogen™ TRIB1 Polyclonal Antibody
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Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5142357

Product Code. 17848222

  • € 465.00 / 100µL

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Description

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

TRIB1 also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRIB1
Polyclonal
Unconjugated
TRIB1
A530090O15Rik; C8FW; Gig2; GIG-2; G-protein-coupled receptor induced protein; G-protein-coupled receptor induced protein GIG2; G-protein-coupled receptor-induced gene 2 protein; G-protein-coupled receptor-induced protein 2; phosphoprotein regulated by mitogenic pathways; SKIP1; Trb1; TRB-1; Trib1; tribbles homolog 1; tribbles homolog 1 (Drosophila); tribbles pseudokinase 1; tribbles-like protein 1
Goat
Ammonium Sulfate Precipitation
RUO
10221
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q96RU8
TRIB1
Peptide with sequence C-TSDQIVPEYQEDSD (aa 353-366).
100 μg
Primary
Human
Antibody
IgG
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