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TRIB3 Monoclonal Antibody (OTI2D11), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA807540
This item is not returnable.
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Description
A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.Specifications
| TRIB3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q96RU7 | |
| TRIB3 | |
| Human recombit protein fragment corresponding to amino acids 1-200 of human TRIB3 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin) | |
| OTI2D11 | |
| Unconjugated | |
| TRIB3 | |
| C20orf97, NIPK, SINK, SKIP3, TRB3 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 57761 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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