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Trimethylsilyl azide, 94%
Description
Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis.
Solubility
Miscible with toluene, dichloromethane, diethyl ether and most organic solvents.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
Specifications
Specifications
| Melting Point | -95°C |
| Density | 0.872 |
| Boiling Point | 95°C to 99°C |
| Flash Point | 6°C (42°F) |
| Refractive Index | 1.414 |
| Quantity | 5 g |
| UN Number | UN1992 |
| Beilstein | 1903730 |
| Sensitivity | Moisture sensitive |
| Solubility Information | Miscible with toluene,dichloromethane,diethyl ether and most organic solvents. |
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Safety and Handling
- Trimethylsilyl azide
- Danger
- Acute toxicity Category 3
- LONG-TERM AQUATIC HAZARD Chronic 1
- ACUTE AQUATIC Acute 1
- Flammable liquid Category 2
- H225-Highly flammable liquid and vapour.
- H301-Toxic if swallowed.
- H311-Toxic in contact with skin.
- H331-Toxic if inhaled.
- H400-Very toxic to aquatic life.
- H410-Very toxic to aquatic life with long lasting effects.
- EUH029-Contact with water liberates toxic gas.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P273-Avoid release to the environment.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- MIXTURE LIST-Contains : Trimethylsilyl azide
RUO – Research Use Only
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