missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Trimetrexate, MedChemExpress

Trimetrexate, MedChemExpress

Product Code. 16476627
Encompass_Preferred
Change view
Click to view available options
Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
3 product options available for selection
Product selection table with 3 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16476627 5 mg 5mg
16470267 50 mg 50mg
16453908 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 3 options available.
3 options
This item is not returnable. View return policy
Product Code. 16476627 Supplier Medchem Express Supplier No. HY10373

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.

Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.

Specifications

Chemical Name or Material Trimetrexate
Physical Form Solid
CAS 52128-35-5
Color Yellow
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C19H23N5O3
For Use With (Application) COVID-19-immunoregulation
Synonym CI-898
Solubility Information DMSO : ≥ 61.5 mg/mL (166.48 mM)
SMILES NC1=C(C(C)=C2CNC3=CC(OC)=C(OC)C(OC)=C3)C(C=C2)=NC(N)=N1
Molecular Weight (g/mol) 369.42
Formula Weight 369.42
Percent Purity 99.22%
Grade Research
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.