missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Description
Immunogen sequence: PQQLPAQPPQ QYQASNYPAQ TYTAQTSQPT NYTVAPASQP GMAPSQPGAY QPRPGFTSLP GSTMTPPPSG PNPYARNRPP FGQGYTQPG Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.
TFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.
Specifications
Specifications
| Antigen | TRK fused gene |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | TFG |
| Gene Accession No. | Q92734 |
| Gene Alias | AI173908; HMSNP; protein TFG; SPG57; TF6; TFG; Trk-fused gene; TRK-fused gene protein; TRKT3; TRKT3 oncogene |
| Gene Symbols | TFG |
| Show More |
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?
