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Invitrogen™ TRPC5 Polyclonal Antibody
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Product Code. 16394485 Shop All Thermo Scientific Products
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Quantity:
100 μg
Unit Size:
100µg
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16394485 100 μg 100µg
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Product Code. 16394485 Supplier Invitrogen™ Supplier No. PA595221

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Description

Rabbit Polyclonal Antibody

Human TRPC5 shares 90% amino acid (aa) sequence identity with mouse TRPC5. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HELA whole cell, U87 whole cell, COLO320 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

TRPC5 belongs to the transient receptor family. TRPC5 is one of the seven mammalian TRPC (transient receptor potential channel) proteins. The TRPC5 protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. TRPC5 also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). TRPC5 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, or G-protein coupled receptors. TRPC5 has also been shown to be calcium-selective, and may also be activated by intracellular calcium store depletion. Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPC5
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide
Gene TRPC5
Gene Accession No. Q9UL62
Gene Alias capacitative calcium entry channel 2; CCE2; hTRP5; Htrp-5; mtrp5; PPP1R159; protein phosphatase 1, regulatory subunit 159; short transient receptor potential channel 5; short transient receptor potential channel 5a; transient receptor potential cation channel, subfamily C, member 5a; transient receptor potential cation channel subfamily C member 5; transient receptor potential cation channel subfamily c member 5a; transient receptor potential cation channel, subfamily C, member 5; transient receptor potential cation channel, subfamily C, member 5a; transient receptor potential channel 5; transient receptor protein 5; TRP5; TRP-5; TrpC5; trpc5a; trp-related protein 5; Trrp5; vtransient receptor potential cation channel, subfamily C, member 5; wu:fi73f08
Gene Symbols TRPC5
Host Species Rabbit
Immunogen E.coli-derived human TRPC5 recombinant protein (Position: K684-L973).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7224
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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