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TRPV4 Polyclonal Antibody, Invitrogen™

Product Code. 11515023
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
11515023 100 μL 100µL
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Product Code. 11515023 Supplier Invitrogen Supplier No. OSR00136W

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Description

Rabbit Polyclonal Antibody

Glycerol (1:1) may be added for additional stability. Reconstitute in 100 μL of sterile water.

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPV4
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Gene TRPV4
Gene Accession No. Q9HBA0, Q9EPK8, Q9ERZ8
Gene Alias Transient receptor potential cation channel subfamily V member 4, TrpV4, osm-9-like TRP channel 4, OTRPC4, Vanilloid receptor-like channel 2, Vanilloi
Gene Symbols TRPV4
Host Species Rabbit
Immunogen A synthetic peptide from aa region 300-400 of mouse TRPV4 conjugated to an immunogenic carrier protein was used as the antigen
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 59341, 63873, 66026
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG
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