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Invitrogen™ TSC22D1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA567456
This item is not returnable.
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Description
Immunogen sequence: QYGQQQPMVST QMAPGHVKSV TQNPASEYVQ QQPILQTAMS SGQPSSAGVG AGTTVIPVAQ PQGIQLPVQP TAVPAQPAGA SVQP Highest antigen sequence identity to the following orthologs - mouse 74%, rat 78%.
TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.
Specifications
| TSC22D1 | |
| Polyclonal | |
| Unconjugated | |
| Tsc22d1 | |
| AA589566; AW105905; Cerebral protein 2; Egr5; hucep-2; Kiaa1994; Ptg-2; regulatory protein Tsc22; Regulatory protein TSC-22; RP11-269C23.2; short tandem repeat locus PEZ20 variant 19; Tgfb1i4; TGFbeta-stimulated clone 22; Tgfb-stimulated clone 22 homolog; Tilz1b; transcriptional regulator TSC-22; transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta stimulated clone 22; transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TS22A; Tsc; Tsc22; TSC-22; TSC22 domain family member 1; TSC22 domain family protein 1; TSC22 domain family, member 1; TSC22D1; Tsc22-related inducible leucine zipper 1b | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 8848 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ChIP Assay, Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q15714 | |
| Tsc22d1 | |
| Recombinant Human TSC22. Recombinant protein control fragment (Product #RP-108113). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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