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Invitrogen™ TSC22D4 Polyclonal Antibody
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Product Code. 15770291 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15770291 100 μL 100µL
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Product Code. 15770291 Supplier Invitrogen™ Supplier No. PA552342

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TPLPSLRVEA EAGGSGARTP PLSRRKAVDM RLRMELGAPE EMGQVPPLDS RPSSPALYFT HDASLVHKSP DPFGAVAAQK FSLAHSMLAI SGHLDSDDDS GSGSLVGIDN KIEQAMDLVK SHLMF Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TSC22D1. Binds DNA and acts as a transcriptional repressor (PubMed:10488076). Involved in the regulation of systematic glucose homeostasis and insulin sensitivity, via transcriptional repression of downstream insulin signaling targets such as OBP2A/LCN13 (By similarity). Acts as a negative regulator of lipogenic gene expression in hepatocytes and thereby mediates the control of very low-density lipoprotein release (PubMed:23307490). May play a role in neurite elongation and survival (By similarity).
TRUSTED_SUSTAINABILITY

Specifications

Antigen TSC22D4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Tsc22d4
Gene Accession No. Q9Y3Q8
Gene Alias 0610009M14Rik; 1700023B23Rik; AI415410; LOW QUALITY PROTEIN: TSC22 domain family protein 4; THG1; THG-1; Thg1pit; Thg-1pit; Tilz2; TSC22 domain family 4; TSC22 domain family member 4; TSC22 domain family protein 4; TSC22 domain family, member 4; Tsc22d4; tsc-22-like protein THG-1; TSC22-related inducible leucine zipper 2; TSC22-related-inducible leucine zipper protein 2
Gene Symbols Tsc22d4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TSC22D4. Recombinant protein control fragment (Product #RP-89392).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81628
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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