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Invitrogen™ TTI1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA566987

Product Code. 15949664

  • € 566.00 / 100µL

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Description

Description

Immunogen sequence: ERLDLGEGDLN KVADACLIYL SVKQPVKLQE AARSVFLHLM KVDPDSTWFL LNELYCPVQF TPPHPSLHPV QLHGASGQQN PYTT Highest antigen sequence identity to the following orthologs - mouse 85%, rat 83%.

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TTI1
Polyclonal
Unconjugated
TTI1
2610036D13Rik; AI449463; KIAA0406; Protein SMG10; SMG10; smg-10; smg-10 homolog, nonsense mediated mRNA decay factor; Tel two interacting protein 1; Tel2 interacting protein 1 homolog; TEL2-interacting protein 1 homolog; TELO2 interacting protein 1; TELO2-interacting protein 1 homolog; TTI1
Rabbit
Antigen Affinity Chromatography
RUO
9675
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
O43156
TTI1
Recombinant Human TTI1. Recombinant protein control fragment (Product #RP-107631).
100 μL
Primary
Human
Antibody
IgG
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