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Invitrogen™ TTI1 Polyclonal Antibody
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Product Code. 15604785
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Quantity:
100 μL
Unit Size:
100µL
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15604785 100 μL 100µL
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Product Code. 15604785 Supplier Invitrogen™ Supplier No. PA550852

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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total TTI1 protein.

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TTI1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 2.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene TTI1
Gene Accession No. O43156, Q91V83
Gene Alias 2610036D13Rik; AI449463; KIAA0406; Protein SMG10; SMG10; smg-10; smg-10 homolog, nonsense mediated mRNA decay factor; Tel two interacting protein 1; Tel2 interacting protein 1 homolog; TEL2-interacting protein 1 homolog; TELO2 interacting protein 1; TELO2-interacting protein 1 homolog; TTI1
Gene Symbols TTI1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues near the N terminal of human TELO2 interacting protein 1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 75425, 9675
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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