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Tubastatin A, MedChemExpress

Product Code. 16486146
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Product Code. 16486146 Supplier Medchem Express Supplier No. HY13271A

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Description

MedChemExpress Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).

Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).

Specifications

Chemical Name or Material Tubastatin A
CAS 1252003-15-8
Color Off-White
Purity Grade Notes Research
Molecular Formula C20H21N3O2
Quantity 100 mg
Solubility Information DMSO : 12.5 mg/mL (37.27 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(NO)C1=CC=C(CN2C3=C(CN(C)CC3)C4=C2C=CC=C4)C=C1
Molecular Weight (g/mol) 335.4
Formula Weight 335.4
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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