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Invitrogen™ TWEAK Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599204

Product Code. 16643455

  • € 491.00 / 100µL

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Description

Description

Antibody detects endogenous levels of total TWEAK.

TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TWEAK
Polyclonal
Unconjugated
Tnfsf12
APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941
Rabbit
Affinity chromatography
RUO
21944, 8742
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O43508, O54907
Tnfsf12
A synthesized peptide derived from human TNFSF12(Accession O43508), corresponding to amino acid residues M1-L35.
100 μL
Primary
Human, Mouse
Antibody
IgG
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