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Invitrogen™ Human TYK2, GST Tag Recombinant Protein

Product Code. 10546635
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Quantity:
10 μg
100 μg
Unit Size:
100µg
Each
This item is not returnable. View return policy

Product Code. 10546635

Brand: Invitrogen™ PV4790

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Cytoplasmic, Catalytic.

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P29597
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 0.02% Triton X-100, 50% glycerol, 2mM DTT, 0.5mM EDTA, 150mM NaCl and no preservative; pH 7.5
Gene ID (Entrez) 7297
Molecular Weight (g/mol) 68.8 kDa
Name Human TYK2, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; IMD35; JTK1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2; tyrosine kinase TYK2
Common Name TYK2
Gene Symbol TYK2
KinaseFamily JAK Kinase Family
Protein Length 833-1187
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 833-1187
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group Tyrosine Kinases
Shipping Condition Dry Ice
System Compatibility LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Tag Position N-Terminal
Target Entry TYK2
Target Gene tyrosine kinase 2
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Cytoplasmic, Catalytic
Form Liquid
Protein Subtype Cytoplasmic Tyrosine Kinases
Research Category Signal Transduction
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