missing translation for 'onlineSavingsMsg'
Learn More
Learn More
TYMS Monoclonal Antibody (OTI1A6), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA801678
This item is not returnable.
View return policy
Description
Thymidylate Synthase (TS) (EC 2.1.1.45) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.Specifications
| TYMS | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P04818 | |
| TYMS | |
| Full length human recombit protein of human TYMS produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI1A6 | |
| Unconjugated | |
| TYMS | |
| HST422, TMS, TS | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 7298 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Korrigering av produktinnehåll
Fisher Scientific Encompass-programmet erbjuder artiklar som inte ingår i vår distributionsportfölj. Dessa produkter har vanligtvis inga bilder eller detaljerade beskrivningar. Vi är dock angelägna om att förbättra din shoppingupplevelse. Använd formuläret nedan för att ge feedback relaterad till innehållet på denna produkt.
Produkttitel
Hittar du en möjlighet till förbättring?Dela en innehållskorrigering