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TYRO3 Mouse anti-Human, Clone: OTI4C8, lyophilized, TrueMAB™

Product Code. 17610501
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Quantity:
100 μg
Unit Size:
100µg
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17610501 100 μg 100µg
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Product Code. 17610501 Supplier Origene Technologies Supplier No. CF500416

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, and cytoskeleton reorganization.

Specifications

Antigen TYRO3
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone OTI4C8
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene TYRO3
Gene Accession No. Q06418
Gene Alias BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif
Gene Symbols TYRO3
Host Species Mouse
Immunogen Full length human recombit protein of human TYRO3 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7301
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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