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  7. Tyrphostin AG 879, MedChemExpress

Tyrphostin AG 879, MedChemExpress

Product Code. 16443736
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Product Code. 16443736 Supplier Medchem Express Supplier No. HY20878

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Description

MedChemExpress Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity.

Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity.

Specifications

Chemical Name or Material Tyrphostin AG 879
CAS 148741-30-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C18H24N2OS
Quantity 25 mg
Synonym AG 879
Solubility Information DMSO : 50 mg/mL (158.00 mM; Need ultrasonic)
SMILES S=C(N)/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
Molecular Weight (g/mol) 316.46
Formula Weight 316.46
Percent Purity 99.54%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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