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U2AF1L4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA566408
Additional Details : Weight : 0.01000kg
Description
Immunogen sequence: PRGSILATIPE RGTIGVPLIT GMAASEALAP LPFTPNRDRC SWQDLSSKP Highest antigen sequence identity to the following orthologs - mouse 33%, rat 32%.
RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site. Shows a preference for AGC or AGA. [UniProt]Specifications
| U2AF1L4 | |
| Polyclonal | |
| Unconjugated | |
| U2AF1L4 | |
| FLJ35525; MGC33901; Splicing factor U2AF 26 kDa subunit; U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1 like 4; U2 small nuclear RNA auxiliary factor 1-like 3; U2 small nuclear RNA auxiliary factor 1-like 4; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like 3; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3; U2AF1L3; U2AF1L3V1; U2AF1L4; U2AF1-like 4; U2AF1-like protein 3; U2AF1RS3; U2AF1-RS3; U2af26 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 199746 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q8WU68 | |
| U2AF1L4 | |
| Recombinant Human U2AF1L4 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
For Research Use Only