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DiscoverX U2OS OXGR1 Gq Cell Line

Product Code. 17314749
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17314749

Brand: DiscoverX 951017C3

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This item is not returnable. View return policy

Description

The U2OS OXGR1 Gq Cell Line measures OXGR1 (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.

The OXGR1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-ketoglutarate) based activation of OXGR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses OXGR1 , a naturally Gq coupled GPCR. Upon activation of OXGR1 , the resulting calcium activity can be fluorescently assayed using the Calcium NoWash PLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Calcium Signaling
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist α-ketoglutarate
Quantity 2 Vials
Target Entry OXGR1
Accession Number NM_080818.3
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