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UBA3 Monoclonal Antibody (OTI1B9), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA811881
This item is not returnable.
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Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Specifications
| UBA3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q8C878, Q8TBC4, Q99MI7 | |
| UBA3 | |
| Human recombit protein fragment corresponding to amino acids 1-463 of human UBA3 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Canine, Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI1B9 | |
| Unconjugated | |
| UBA3 | |
| NAE2, UBE1C, hUBA3 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 117553, 22200, 476560, 9039 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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