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Invitrogen™ UBE2C Polyclonal Antibody
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Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5142493

Product Code. 17836332

  • € 465.00 / 100µL

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Description

Description

Additional Information: This antibody is expected to recognize isoforms 1 (NP_008950.1), 2 ( NP_861515.1) and 4 (NP_861517.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

UBE2C
Polyclonal
Unconjugated
UBE2C
(E3-independent) E2 ubiquitin-conjugating enzyme C; 1110015A16Rik; cyclin-selective ubiquitin carrier protein; D2Ertd695e; dJ447F3.2; E2 ubiquitin-conjugating enzyme C; mitotic-specific ubiquitin-conjugating enzyme; RP3-447F3.1; ubcH10; UBE2C; Ubiquitin carrier protein C; ubiquitin conjugating enzyme E2 C; ubiquitin conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; ubiquitin-conjugating enzyme E2C; ubiquitin-protein ligase C
Goat
Ammonium sulfate precipitation
RUO
11065
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
O00762
UBE2C
Peptide with sequence C-SGDKGISAFPESDN.
100 μg
Primary
Human
Antibody
IgG
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