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Invitrogen™ UBE2L3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA530202

Product Code. 13474517

€ 516.00 / 100µL

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Description

Recommended positive controls: 293T, HeLa, JurKat, mouse testis, UBE2L3 shRNA-transfected 293T. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (99%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.

Specifications

Antigen	UBE2L3
Classification	Polyclonal
Conjugate	Unconjugated
Gene	UBE2L3
Gene Alias	C79827; E2 ubiquitin-conjugating enzyme L3; E2-F1; L-UBC; UBCE7; UBCH7; UbcM4; Ube2l3; Ubiquitin carrier protein L3; ubiquitin conjugating enzyme E2 L3; ubiquitin conjugating enzyme E2L 3; ubiquitin-conjugating enzyme 7; ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme E2L 3; ubiquitin-conjugating enzyme UBCH7; ubiquitin-protein ligase L3; Unknown (protein for MGC:127956)
Host Species	Rabbit
Purification Method	Antigen affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	22195, 7332
Content And Storage	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form	Liquid

Applications	Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Concentration	0.78 mg/mL
Formulation	0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.	P68036, P68037
Gene Symbols	UBE2L3
Immunogen	Recombinant protein encompassing a sequence within the center region of human UBE2L3. The exact sequence is proprietary.
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse
Product Type	Antibody
Isotype	IgG

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Invitrogen™ UBE2L3 Polyclonal Antibody

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