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Invitrogen™ UCP1 Polyclonal Antibody
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Product Code. 17762354
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Quantity:
100 μL
Unit Size:
100µL
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17762354 100 μL 100µL
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Product Code. 17762354 Supplier Invitrogen™ Supplier No. PA5120958

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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse kidney, HL-60, Rat lung. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein.

Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins. UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UCP1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.68 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene Ucp1
Gene Accession No. P04633, P12242
Gene Alias AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product
Gene Symbols Ucp1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22227, 24860
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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