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Invitrogen™ UMPS Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA589118
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Description
Immunogen sequence: TKDYGTKRLV EGTINPGETC LIIEDVVTSG SSVLETVEVL QKEGLKVTDA IVLLDREQGG KDKLQAHGIR LHSVCTLSKM LEILEQQKKV DAETVGRVKR FIQENVFVAA NHNGSPLSIK EAPKELSFGA RAELPRIHPV ASKLLRLMQK KETNLCLSAD V; Positive Samples: HT-29, U-87MG, HeLa, LO2, Mouse brain, Mouse kidney.
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Specifications
| UMPS | |
| Polyclonal | |
| Unconjugated | |
| UMPS | |
| 1700095D23Rik; AA408257; AL033308; BB164745; mutant uridine monophosphate synthase; ODC; OK/SW-cl.21; OMPdecase; OPRT; OPRTase; orotate phosphoribosyl transferase and orotidine-5'-decarboxylase; orotate phosphoribosyltransferase; Orotidine 5'-phosphate decarboxylase; UMP synthase; UMPS; Uridine 5'-monophosphate synthase; uridine 5-monophosphate synthase; uridine 5'-monophosphate synthase-like protein; uridine monophophate synthase; uridine monophosphate synthase; uridine monophosphate synthetase; uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase); uridine monophosphate synthetase [orotate phosphoribosyl transferase and orotidine-5'-decarboxylase] | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 22247, 288051, 7372 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot, Immunocytochemistry | |
| 3.33 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| P11172, P13439 | |
| UMPS | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human UMPS (NP_0003641). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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