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UNC2025 hydrochloride, MedChemExpress

Product Code. 16495108
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Product Code. 16495108

Brand: Medchem Express HY12344A

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Description

MedChemExpress UNC2025 hydrochloride is a potent, ATP-competitive, and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki = 13.3 nM). UNC2025 hydrochloride exhibits an excellent PK properties, and can be used for the investigation of acute leukemia.

UNC2025 hydrochloride is a potent, ATP-competitive, and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 hydrochloride is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM

Specifications

Chemical Name or Material UNC2025 hydrochloride
CAS 2070015-17-5
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C28H41ClN6O
Quantity 10 mg
Solubility Information H2O : 55 mg/mL (107.19 mM; Need ultrasonic) ∣DMSO : 10 mg/mL (19.49 mM; Need ultrasonic)
SMILES CN1CCN(CC2=CC=C(C3=CN([C@@H]4CC[C@@H](O)CC4)C5=NC(NCCCC)=NC=C53)C=C2)CC1.[H]Cl
Molecular Weight (g/mol) 513.12
Formula Weight 513.12
Percent Purity 99.41%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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