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Invitrogen™ UNC5C Polyclonal Antibody

Description
Positive test controls include: SH-SY5Y, 293T, Mouse brain, Mouse lung, Rat brain. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, synapse, synaptosome.
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin -like domains and 2 type I thrombospondin motifs in the extracellular region.
Specifications
Specifications
| Antigen | UNC5C |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 1.6 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | Unc5c |
| Gene Accession No. | O08747, O95185, Q761X5 |
| Gene Alias | B130051O18Rik; Netrin receptor UNC5C; protein unc-5 homolog 3; Protein unc-5 homolog C; Rcm; Rostral cerebellar malformation protein; unc5 (C.elegans homolog) c; unc5 homolog 3; UNC-5 homolog 3; unc-5 homolog C; unc-5 homolog C (C. elegans); unc-5 netrin receptor C; UNC5C; UNC5H3 |
| Gene Symbols | Unc5c |
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