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Invitrogen™ UNC5CL Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582536

Product Code. 16389494

  • € 524.00 / 100µL

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Description

Description

Immunogen sequence: MHTFQDGLET KYMEILRFQA SEEESWAAPP PVSQPPPCNR LPPELFEQLR MLLEPNSITG NDWRRLASHL GLCGMKIRFL SCQRSPAAAI LELFEEQNGS LQELHYLMTV MERLDCASAI QNYLSGTHGG SPGPERGGAR DNQGLELDEK Highest antigen sequence indentity to the following orthologs: Rat - 87%, Mouse - 87%.

UNC5CL is a membrane protein belonging to theUNC-5 family with a death domain and a ZU5 domain and is known to interact with p65/RELA and NFKB1. UNC5CL is known to interact with subunit p105 of NF-kappaB and transactivator p65 and is thus involved in inhibition of NF-kappaB activation and NF-kappaB-dependent transcription by inhibiting the binding of NF-kappaB to its target sequence (providing an alternative regulatory mechanism for NF-kappaB-mediated transcription). This regulatory protein sensitizes cells to apoptosis induced by TNF and TRAIL.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

UNC5CL
Polyclonal
Unconjugated
UNC5CL
2510009H09Rik; BB155270; MGC34763; MUXA; OTTHUMP00000016362; protein unc-5 homolog C-like; unc-5 family C-terminal like; unc-5 homolog C (C. elegans)-like; UNC5CL; UNC5C-like protein; zu-5; ZU5 and death domain containing; ZU5 and death domain-containing inhibitor of NF-kB; ZU5 and death domain-containing protein; ZUD
Rabbit
Antigen affinity chromatography
RUO
222643
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q8IV45
UNC5CL
Recombinant protein corresponding to Human UNC5CL. Recombinant protein control fragment (Product #RP-90179).
100 μL
Primary
Human
Antibody
IgG
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