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Invitrogen™ USP12 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5139844
This item is not returnable.
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Description
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: RLPNGNIDNE NNNSTPDPTW VHEI Highest antigen sequence indentity to the following orthologs: Mouse - 83%, Rat - 79%.
Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProt].
Specifications
| USP12 | |
| Polyclonal | |
| Unconjugated | |
| USP12 | |
| Deubiquitinating enzyme 12; UBH1; Ubiquitin carboxyl-terminal hydrolase 12; ubiquitin hydrolyzing enzyme 1; ubiquitin specific peptidase 12; ubiquitin specific protease 12; ubiquitin specific protease 12 like 1; ubiquitin thioesterase 12; ubiquitin thiolesterase 12; ubiquitin-hydrolyzing enzyme 1; Ubiquitin-specific-processing protease 12; Usp12; USP12L1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 219333 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O75317 | |
| USP12 | |
| Recombinant protein corresponding to Human USP12. Recombinant protein control fragment (Product #RP-108970). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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