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Invitrogen™ UVRAG Polyclonal Antibody
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Product Code. 15367624
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Quantity:
400 μL
Unit Size:
400µL
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15367624 400 μL 400µL
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Product Code. 15367624 Supplier Invitrogen™ Supplier No. PA535213

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Description

Rabbit Polyclonal Antibody

UVRAG Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

UVRAG is predicted to contain a coiled-coil structure and is likely to be metabolically unstable based on the occurrence of a strong PEST domain. It interacts with Beclin 1, leading to activation of autophagy and thereof inhibition of tumorigenicity of human colon cancer cells. The gene for UVRAG protein is localized on human chromosome 11q13. 5 and complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells. The gene has been extremely well conserved during evolution, implying an important role for this gene product in cell metabolism. Chromosomal aberrations involving this gene are associated with left-right axis malformation, and mutations in this gene have been associated with colon cancer. The protein is highly expressed in human brain, lung, kidney and liver.
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Specifications

Antigen UVRAG
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Uvrag
Gene Accession No. Q8K245, Q9P2Y5
Gene Alias 9530039D02Rik; AI648770; BB124205; beclin 1 binding protein; DHTX; disrupted in heterotaxy; hypothetical protein; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance-associated gene protein; UV radiation resistance-associated protein; UVRAG; Uvrag1; Uvragl; VPS38
Gene Symbols Uvrag
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 666-699 amino acids from the C-terminal region of human UVRAG.
Purification Method Ammonium Sulfate Precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7405, 78610
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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