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Invitrogen™ V-ATPase H Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA554793
This item is not returnable.
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Description
Immunogen sequence: PQVLAVAAHD VGEYVRHYPR GKRVIEQLGG KQLVMNHMHH EDQQVRYNAL LAVQKLMVHN WEYLGKQLQS E Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Specifications
| V-ATPase H | |
| Polyclonal | |
| Unconjugated | |
| ATP6V1H | |
| 0710001F19Rik; Atp6v1h; ATPase H+ transporting V1 subunit H; ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H; ATPase, H+ transporting, lysosomal V1 subunit H; AU022349; CGI-11; MSTP042; NBP1; Nef-binding protein 1; protein VMA13 homolog; SFD; SFDalpha; SFDbeta; vacuolar ATP synthase subunit H; vacuolar ATPase subunit H; vacuolar proton pump H subunit; vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD; V-ATPase 50/57 kDa subunits; V-ATPase H subunit; V-ATPase subunit H; VMA13; V-type proton ATPase subunit H | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 51606 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9UI12 | |
| ATP6V1H | |
| Recombinant protein corresponding to Human V-ATPase H. Recombinant protein control fragment (Product #RP-93733). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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