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Vactosertib, MedChemExpress

Product Code. 16480428
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Product Code. 16480428

Brand: Medchem Express HY19928

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Description

MedChemExpress Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect.

Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect.

Specifications

Chemical Name or Material Vactosertib
CAS 1352608-82-2
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C22H18FN7
Quantity 5 mg
Synonym EW-7197 TEW-7197
Solubility Information DMSO : 100 mg/mL (250.36 mM; Need ultrasonic)
SMILES CC1=CC=CC(C2=C(C3=CN4C(C=C3)=NC=N4)NC(CNC5=CC=CC=C5F)=N2)=N1
Molecular Weight (g/mol) 399.42
Formula Weight 399.42
Percent Purity 98.27%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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