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Invitrogen™ VAMP4 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA592171

Product Code. 16538161

  • € 520.00 / 100µL

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Description

Description

Immunogen sequence: MPPKFKRHLN DDDVTGSVKS ERRNLLEDDS DEEEDFFLRG PSGPRFGPRN DKIKHVQNQV DEVIDVMQEN ITKVIERGER LDELQDKSES LSDNATAFSN RSKQLRRQMW WRGCK; Positive Samples: B cells, HeLa, Jurkat, BT-474, NIH/3T3, Mouse brain, Mouse lung, Rat brain; Cellular Location: Golgi apparatus, Single-pass type IV membrane protein, trans-Golgi network membrane.

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

VAMP4
Polyclonal
Unconjugated
VAMP4
D1Ertd147e; vamp; VAMP24; VAMP4; VAMP-4; vesicle associated membrane protein 4; vesicle-associated membrane protein 4
Rabbit
Affinity chromatography
RUO
364033, 53330, 8674
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
2.45 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O70480, O75379
VAMP4
Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human VAMP4 (NP_0037532).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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