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Invitrogen™ VAV1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA581980
This item is not returnable.
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Description
Immunogen sequence: LSWTPIAQNR GIMPFPTEEE SVGDEDIYSG LSDQIDDTVE EDEDLYDCVE NEEAEGDEIY EDLMRSEPVS MPPKMTEYDK RCCCLREIQQ TEEKYTDTLG SIQQHFLKPL QRFLKPQDIE IIFINIEDLL RVHTHFLKEM KEAL Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 88%.
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
Specifications
| VAV1 | |
| Polyclonal | |
| Unconjugated | |
| VAV1 | |
| oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 7409 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P15498 | |
| VAV1 | |
| Recombinant protein corresponding to Human VAV1. Recombinant protein control fragment (Product #RP-94785). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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