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  6. Invitrogen™ VE-cadherin Recombinant Rabbit Monoclonal Antibody (9W5E3)

Invitrogen™ VE-cadherin Recombinant Rabbit Monoclonal Antibody (9W5E3)
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Product Code. 30283805
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30283805 100 μL 100µL
30283575 20 μL 20µL
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Product Code. 30283805 Supplier Invitrogen™ Supplier No. MA557860

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: DWIWNQMHID EEKNTSLPHH VGKIKSSVSR KNAKYLLKGE YVGKVFRVDA ETGDVFAIER LDRENISEYH LTAVIVDKDT GENLETPSSF TIKVHDVNDN WPVFTHRLFN ASVPESSAVG TSVISVTAVD ADDPTVGDHA SVMYQILKGK EYFAIDNSGR IITITKSLDR EKQARYEIVV EARDAQGLRG DSGTATVLVT LQDINDNFPF FTQTKYTFVV PEDTRVGTSV GSLFVEDPDE PQNRMTKYSI LRGDYQDAFT IETNPAHNEG IIKPMKPLDY EYIQQYSFIV EATDPTIDLR YMSPPAGNRA QVIINITDVD EPPIFQQPFY HFQLKENQKK PLIGTVLAMD PDAARHSIGY SIRRTSDKGQ FFRVTKKGDI YNEKELDREV YPWYNLTVEA KELDSTGTPT GKESIVQVHI EVLDENDNAP EFAKPYQPKV CENAVHGQLV LQISAIDKDI TPRNVKFKFI LNTENNFTLT DNHDNTANIT VKYGQFDREH TKVHFLPVVI SDNGMPSRTG TSTLTVAVCK CNEQGEFTFC EDMAAQ.

VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VE-cadherin
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 9W5E3
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene CDH5
Gene Accession No. P33151
Gene Alias 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Gene Symbols CDH5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 48-593 of human VE Cadherin (NP_001786.2).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1003
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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