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Invitrogen™ VEGF Receptor 3 Monoclonal Antibody (102804)
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Product Code. 30533832
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Quantity:
500 μg
Unit Size:
500µg
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Product Code. Quantity unitSize
30533832 500 μg 500µg
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Product Code. 30533832 Supplier Invitrogen™ Supplier No. MA561817

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Description

Rat Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VEGF Receptor 3
Applications ELISA
Classification Monoclonal
Clone 102804
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and no preservative
Gene FLT4
Gene Accession No. P35917
Gene Alias AI323512; Chy; chylous ascites; Flt4; FLT-4; FLT41; fms related tyrosine kinase 4; FMS-like tyrosine kinase 4; fms-related tyrosine kinase 4; LMPH1A; PCL; receptor protein tyrosine kinase; soluble VEGFR 3; sVEGFR 3; tyrosine-protein kinase receptor FLT4; Vascular endothelial growth factor receptor 3; vascular endothelial growth factor receptor-3; VEGF R3; VEGFR3; VEGFR-3
Gene Symbols FLT4
Host Species Rat
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse VEGFR3/Flt-4, Tyr25-Asp770.
Purification Method Protein A/G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14257
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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