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Vismodegib, MedChemExpress

Product Code. 16460327
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Product Code. 16460327 Supplier Medchem Express Supplier No. HY10440

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Description

MedChemExpress Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively.

Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively.

Specifications

Chemical Name or Material Vismodegib
CAS 879085-55-9
Color Off-White
Purity Grade Notes Research
Molecular Formula C19H14Cl2N2O3S
Quantity 50 mg
Synonym GDC-0449
Solubility Information DMSO : 50 mg/mL (118.68 mM; Need ultrasonic) ∣Ethanol : 3.33 mg/mL (7.90 mM; ultrasonic and warming and heat to 60°C)
SMILES O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl
Molecular Weight (g/mol) 421.3
Formula Weight 421.3
Percent Purity 95.75%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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