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Invitrogen™ VNN1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA575160
This item is not returnable.
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Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.
Specifications
| VNN1 | |
| Polyclonal | |
| Unconjugated | |
| VNN1 | |
| HDLCQ8; Pantetheinase; pantetheine hydrolase; Tiff66; V-1; vanin 1; Vanin1; vanin-1; vannin 1; vascular non-inflammatory molecule 1; VNN1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 22361, 8876 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| O95497, Q9Z0K8 | |
| VNN1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 300-415 of human VNN1. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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