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Invitrogen™ VPS35 Monoclonal Antibody (10A8), APC

Description
A 1:1,000 dilution of MA5-45945 was sufficient for detection of VPS35 in 10 μg of SH-SY5Y by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody. Detects approximately 92 kDa.
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.
Specifications
Specifications
| Antigen | VPS35 |
| Applications | Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 10A8 |
| Concentration | 1 mg/mL |
| Conjugate | APC |
| Formulation | 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4 |
| Gene | VPS35 |
| Gene Accession No. | Q96QK1, Q9EQH3 |
| Gene Alias | AI647796; DKFZp434E1211; DKFZp434P1672; FLJ10752; FLJ13588; FLJ20388; hVPS35; Maternal embryonic message 3; maternal-embryonic 3; Mem3; PARK17; TCCCTA00141; vacuolar protein sorting 35; vacuolar protein sorting 35 homolog; vacuolar protein sorting 35 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 35; Vesicle protein sorting 35; VPS35; VPS35 retromer complex component |
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