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Invitrogen™ VPS39 Polyclonal Antibody
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Product Code. 16557031
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Quantity:
100 μL
Unit Size:
100µL
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16557031 100 μL 100µL
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Product Code. 16557031 Supplier Invitrogen™ Supplier No. PA588969

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RFHNCLIQLY CEKVQGLMKE YLLSFPAGKT PVPAGEEEGE LGEYRQKLLM FLEISSYYDP GRLICDFPFD GLLEERALLL GRMGKHEQAL FIYVHILKDT RMAEEYCHKH YDRNKDGNKD VYLSLLRMYL SPPSIHCLGP IKLELLEPKA NLQAALQVLE LHHSKLDTTK ALNLLPANTQ INDIRIFLEK VLEENAQKKR FNQVLKNLLH AEFLRVQEER ILHQQVKCII TEEKVCMVCK KKIGNSAFAR YPNGVVVHYF CSKEVNPADT; Positive Samples: U-87MG, 293T, A-549; Cellular Location: Cytoplasm, Late endosome, Late endosome membrane, Lysosome, Lysosome membrane, Peripheral membrane protein.

VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6. 5.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS39
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.01 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene VPS39
Gene Accession No. Q8R5L3, Q96JC1
Gene Alias A230065P22Rik; AW743070; hVam6p; KIAA0770; mVam6; OTTMUSP00000023341; OTTMUSP00000023350; PI3K type 3; Pldn; TLP; TRAP1-like protein; vacuolar protein sorting 39 (yeast); vacuolar protein sorting 39 homolog; vacuolar protein sorting 39 homolog (S. cerevisiae); Vam6; Vam6/Vps39-like protein; Vam6P; Vps39; VPS39 HOPS complex subunit; VPS39, HOPS complex subunit
Gene Symbols VPS39
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 606-875 of human VPS39 (NP_0561042).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23339, 269338, 362199
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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