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Tocris Bioscience™ VU 0360172 hydrochloride

Product Code. 30001483
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30001483 10 mg 10mg
30001491 50 mg 50mg
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Product Code. 30001483 Supplier Tocris Bioscience™ Supplier No. 4323/10

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200.60 EUR valid until 2026-03-31
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Description

Positive allosteric modulator of mGlu5 receptors

Positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM). Selective for mGlu5; displays no significant activity at mGlu1, mGlu2 or mGlu4 receptors. Exhibits antipsychotic-like activity in a rodent model. Also reduces spontaneous spike and wave discharges without affecting motor behaviour in a rat model of absence epilepsy.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1309976-62-2
Molecular Formula C18H16ClFN2O

Specifications

Quantity 10 mg
Formula Weight 330.78
Purity >98%
Molecular Weight (g/mol) 330.787
Chemical Name or Material VU 0360172 hydrochloride
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