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Invitrogen™ WDR4 Recombinant Rabbit Monoclonal Antibody (5R7B6)
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Product Code. 17236863 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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17236863 100 μL 100µL
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Product Code. 17236863 Supplier Invitrogen™ Supplier No. MA537987

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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, HepG2, A-549, Mouse lung, Mouse spleen, Mouse kidney, Rat kidney Immunogen sequence: AFWCQENCVA LLCDGTPVVY IFQLDARRQQ LVYRQQLAFQ HQVWDVAFEE TQGLWVLQDC QEAPLVLYRP VGDQWQSVPE STVLKKVSGV LRGNWAMLEG S.

Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WDR4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 5R7B6
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Gene WDR4
Gene Accession No. P57081, Q9EP82
Gene Alias AI415180; AI448349; D530049K22Rik; hWH; mWH; Protein Wuho homolog; TRM82; TRM82 tRNA methyltransferase 82 homolog; TRMT82; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat domain 4; WD repeat-containing protein 4; WD40 repeat protein 4; WDR4
Gene Symbols WDR4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 250-350 of human WDR4 (P57081).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10785, 57773, 690032
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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