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Invitrogen™ WEE1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA595636
Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human placenta tissue, human A431 whole cell, human U2OS whole cell. IHC: human mammary cancer tissue. ICC/IF: U20S cell. Flow: SiHa cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Specifications
| WEE1 | |
| Polyclonal | |
| Unconjugated | |
| WEE1 | |
| CTRCT30; DKFZp686I18166; epididymis luminal protein 113; fa20h03; FLJ16446; HEL113; VIM; Vimentin; wee 1 homolog; WEE 1 homolog 1 (S. pombe); Wee1; WEE1 G2 checkpoint kinase; WEE1 homolog; wee1 protein; WEE1 tyrosine kinase; WEE1+ homolog; Wee1A; wee1A kinase; WEE1hu; wee1-like protein kinase; wu:fa20h03; zgc:136514 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 22390, 308937, 7465 | |
| -20°C | |
| Lyophilized |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 500 μg/mL | |
| PBS with 4mg trehalose and 0.05mg sodium azide | |
| P30291, P47810, Q63802 | |
| WEE1 | |
| A synthetic peptide corresponding to a sequence of human WEE1 (ELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDR). | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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