missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ WEE2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5140078
This item is not returnable.
View return policy
Description
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: DIDKELRQKL NFSYCEETEI EGQKKVEESR EASSQTPEKG EVQDSEAKGT PPWTPLSNVH ELDTSSEKDK ESPDQILRTP VSHPLKC Highest antigen sequence indentity to the following orthologs: Rat - 41%, Mouse - 43%.
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300). Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation. [UniProt].
Specifications
| WEE2 | |
| Polyclonal | |
| Unconjugated | |
| WEE2 | |
| Gm1065; mWee1B; WEE1 homolog 2 (S. pombe); WEE1B; Wee1B kinase; wee1-like protein kinase 1B; Wee1-like protein kinase 2; Wee2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 494551 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P0C1S8 | |
| WEE2 | |
| Recombinant protein corresponding to Human WEE2. Recombinant protein control fragment (Product #RP-108910). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction