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Invitrogen™ West Nile Virus Envelope Monoclonal Antibody (GT3029)
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Product Code. 17196563 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17196563 100 μL 100µL
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Product Code. 17196563 Supplier Invitrogen™ Supplier No. MA535917

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Description

Mouse Monoclonal Antibody

West Nile Virus Envelope Monoclonal Antibody for Western Blot, ICC/IF

West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
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Specifications

Antigen West Nile Virus Envelope
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT3029
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Alias West Nile envelope; West Nile Virus; WNV envelope
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of West Nile virus Envelope protein (West Nile virus (strain NY99-IC)). The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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