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Invitrogen™ WNT10A Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA522155
This item is not returnable.
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Description
Recommended positive controls: Molt-4, Raji. Predicted reactivity: Mouse (96%), Rat (97%), Chicken (82%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
Specifications
| WNT10A | |
| Polyclonal | |
| Unconjugated | |
| WNT10A | |
| OODD; Protein Wnt-10a; SSPS; STHAG4; wingless related MMTV integration site 10a; wingless-type MMTV integration site family member 10A; wingless-type MMTV integration site family, member 10A; Wnt family member 10A; Wnt10a | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 80326 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q9GZT5 | |
| WNT10A | |
| Recombinant protein encompassing a sequence within the center region of human WNT10A. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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