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WNT3 Monoclonal Antibody (OTI2A4), TrueMAB™, OriGene

Product Code. 17550273
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100 μL
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17550273 100 μL 100µL
17570273 30 μL 30µL
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Product Code. 17550273 Supplier Origene Technologies Supplier No. TA801868

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Description

Mouse Monoclonal Antibody

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Specifications

Antigen WNT3
Applications Western Blot
Classification Monoclonal
Clone OTI2A4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene WNT3
Gene Accession No. P56703
Gene Alias INT4, TETAMS
Gene Symbols WNT3
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 128-355 of human WNT3 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7473
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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