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WNT3 Mouse anti-Human, Clone: OTI2D4, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies CF801865
This item is not returnable.
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Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.Specifications
| WNT3 | |
| Monoclonal | |
| Unconjugated | |
| WNT3 | |
| INT4, TETAMS | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 7473 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Western Blot | |
| OTI2D4 | |
| PBS with 8% trehalose and no preservative; pH 7.3 | |
| P56703 | |
| WNT3 | |
| Human recombit protein fragment corresponding to amino acids 128-355 of human WNT3 produced in E.coli. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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